Kendall W. Nettles : rechercher sur Z-Library

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Articles (35)
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A Crystal Structure of a Model of the Repeating r(CGG) Transcript Found in Fragile X Syndrome

Dr. Amit Kumar, Dr. Pengfei Fang, Dr. Hajeung Park, Prof. Dr. Min Guo, Prof. Dr. Kendall W. Nettles, Prof. Dr. Matthew D. Disney

Journal:

ChemBioChem

Année:

2011

Langue:

english

Fichier:

PDF, 1.25 MB

english, 2011

Elemental Isomerism: A Boron-Nitrogen Surrogate for a Carbon-Carbon Double Bond Increases the Chemical Diversity of Estrogen Receptor Ligands

Hai-Bing Zhou, Kendall W. Nettles, John B. Bruning, Younchang Kim, Andrzej Joachimiak, Sanjay Sharma, Kathryn E. Carlson, Fabio Stossi, Benita S. Katzenellenbogen, Geoffrey L. Greene, John A. Katzenel

Journal:

Chemistry & Biology

Année:

2007

Langue:

english

Fichier:

PDF, 617 KB

english, 2007

NFκB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses

Nettles, Kendall W, Bruning, John B, Gil, German, Nowak, Jason, Sharma, Sanjay K, Hahm, Johnnie B, Kulp, Kristen, Hochberg, Richard B, Zhou, Haibing, Katzenellenbogen, John A

Journal:

Nature Chemical Biology

Année:

2008

Langue:

english

Fichier:

PDF, 582 KB

english, 2008

Corrigendum: NFκB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses

Nettles, Kendall W, Bruning, John B, Gil, German, Nowak, Jason, Sharma, Sanjay K, Hahm, Johnnie B, Kulp, Kristen, Hochberg, Richard B, Zhou, Haibing, Katzenellenbogen, John A

Journal:

Nature Chemical Biology

Année:

2008

Langue:

english

Fichier:

PDF, 170 KB

english, 2008

Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism

Shiau, Andrew K., Barstad, Danielle, Radek, James T., Meyers, Marvin J., Nettles, Kendall W., Katzenellenbogen, Benita S., Katzenellenbogen, John A., Agard, David A., Greene, Geoffrey L.

Journal:

Natural Structural Biology

Année:

2002

Langue:

english

Fichier:

PDF, 2.30 MB

english, 2002

Insights into PPARγ from structures with endogenous and covalently bound ligands

Nettles, Kendall W

Journal:

Nature Structural and Molecular Biology

Année:

2008

Langue:

english

Fichier:

PDF, 527 KB

english, 2008

Structural plasticity in the oestrogen receptor ligand-binding domain

Dilis, Robert, Hanson, Robert N, Nettles, Kendall W, Bruning, John B, Gil, German, O'Neill, Erin E, Nowak, Jason, Hughs, Alun, Kim, Younchang, DeSombre, Eugene R

Journal:

EMBO reports

Année:

2007

Langue:

english

Fichier:

PDF, 232 KB

english, 2007

Structural plasticity in the oestrogen receptor ligand-binding domain

Nettles, Kendall W, Bruning, John B, Gil, German, O'Neill, Erin E, Nowak, Jason, Guo, Yuee, Kim, Younchang, DeSombre, Eugene R, Dilis, Robert, Hanson, Robert N

Journal:

EMBO reports

Année:

2007

Fichier:

PDF, 41 KB

2007

Partial Agonists Activate PPARγ Using a Helix 12 Independent Mechanism

John B. Bruning, Michael J. Chalmers, Swati Prasad, Scott A. Busby, Theodore M. Kamenecka, Yuanjun He, Kendall W. Nettles, Patrick R. Griffin

Journal:

Structure

Année:

2007

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2007

Influence of the ventral hippocampal formation on plasma vasopressin, hypothalamic-pituitary-adrenal axis, and behavioral responses to novel acoustic stress

Kendall W. Nettles, Christine Pesold, Morris B. Goldman

Journal:

Brain Research

Année:

2000

Langue:

english

Fichier:

PDF, 630 KB

english, 2000

Influence of the hippocampus/subiculum on antidiuretic hormone levels during stress

Morris B. Goldman, Kendall W. Nettles

Journal:

Psychoneuroendocrinology

Année:

1996

Langue:

english

Fichier:

PDF, 322 KB

english, 1996

Conformation-specific affinity purification of proteins using engineered binding proteins: Application to the estrogen receptor

Jin Huang, Akiko Koide, Kendall W. Nettle, Geoffrey L. Greene, Shohei Koide

Journal:

Protein Expression and Purification

Année:

2006

Langue:

english

Fichier:

PDF, 342 KB

english, 2006

Nuclear Receptor Ligands and Cofactor Recruitment: Is There a Coactivator “On Deck”?

Kendall W Nettles, Geoffrey L Greene

Journal:

Molecular Cell

Année:

2003

Langue:

english

Fichier:

PDF, 112 KB

english, 2003

Allosteric Control of Ligand Selectivity between Estrogen Receptors α and β: Implications for Other Nuclear Receptors

Kendall W. Nettles, Jun Sun, James T. Radek, Shubin Sheng, Alice L. Rodriguez, John A. Katzenellenbogen, Benita S. Katzenellenbogen, Geoffrey L. Greene

Journal:

Molecular Cell

Année:

2004

Langue:

english

Fichier:

PDF, 705 KB

english, 2004

Bicyclic core estrogens as full antagonists: synthesis, biological evaluation and structure–activity relationships of estrogen receptor ligands based on bridged oxabicyclic core arylsulfonamides

Zhu, Manghong, Zhang, Chen, Nwachukwu, Jerome C., Srinivasan, Sathish, Cavett, Valerie, Zheng, Yangfan, Carlson, Kathryn E., Dong, Chune, Katzenellenbogen, John A., Nettles, Kendall W., Zhou, Hai-Bing

Journal:

Organic & Biomolecular Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 729 KB

english, 2012

Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases

John D. Laughlin, Jerome C. Nwachukwu, Mariana Figuera-Losada, Lisa Cherry, Kendall W. Nettles, Philip V. LoGrasso

Journal:

Structure

Année:

2012

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2012

Anterior Medial Temporal Lobe Volumes in Polydipsic Schizophrenic Patients with and without Hypo-Osmolemia: A Pilot Study

Daniel J Luchins, Kendall W Nettles, Morris B Goldman

Journal:

Biological Psychiatry

Année:

1997

Langue:

english

Fichier:

PDF, 127 KB

english, 1997

Ligand-binding dynamics rewire cellular signaling via estrogen receptor-α

Srinivasan, Sathish, Nwachukwu, Jerome C, Parent, Alex A, Cavett, Valerie, Nowak, Jason, Hughes, Travis S, Kojetin, Douglas J, Katzenellenbogen, John A, Nettles, Kendall W

Journal:

Nature Chemical Biology

Année:

2013

Langue:

english

Fichier:

PDF, 1.32 MB

english, 2013

Thiophene-Core Estrogen Receptor Ligands Having Superagonist Activity

Min, Jian, Wang, Pengcheng, Srinivasan, Sathish, Nwachukwu, Jerome C., Guo, Pu, Huang, Minjian, Carlson, Kathryn E., Katzenellenbogen, John A., Nettles, Kendall W., Zhou, Hai-Bing

Journal:

Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 2.73 MB

english, 2013

Improved Crystallographic Structures Using Extensive Combinatorial Refinement

Nwachukwu, Jerome C., Southern, Mark R., Kiefer, James R., Afonine, Pavel V., Adams, Paul D., Terwilliger, Thomas C., Nettles, Kendall W.

Journal:

Structure

Année:

2013

Langue:

english

Fichier:

PDF, 2.23 MB

english, 2013

Structure-Guided Optimization of Estrogen Receptor Binding Affinity and Antagonist Potency of Pyrazolopyrimidines with Basic Side Chains

Zhou, Hai-Bing, Sheng, Shubin, Compton, Dennis R., Kim, Younchang, Joachimiak, Andrzej, Sharma, Sanjay, Carlson, Kathryn E., Katzenellenbogen, Benita S., Nettles, Kendall W., Greene, Geoffrey L., Katz

Journal:

Journal of Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 196 KB

english, 2007

Myotonic Dystrophy Type 1 RNA Crystal Structures Reveal Heterogeneous 1 × 1 Nucleotide UU Internal Loop Conformations

Kumar, Amit, Park, HaJeung, Fang, Pengfei, Parkesh, Raman, Guo, Min, Nettles, Kendall W., Disney, Matthew D.

Journal:

Biochemistry

Année:

2011

Langue:

english

Fichier:

PDF, 4.32 MB

english, 2011

Triaryl-Substituted Schiff Bases Are High-Affinity Subtype-Selective Ligands for the Estrogen Receptor

Liao, Zong-Quan, Dong, Chune, Carlson, Kathryn E., Srinivasan, Sathish, Nwachukwu, Jerome C., Chesnut, Robert W., Sharma, Abhishek, Nettles, Kendall W., Katzenellenbogen, John A., Zhou, Hai-Bing

Journal:

Journal of Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 1.77 MB

english, 2014

LIGAND CONTROL OF COREGULATOR RECRUITMENT TO NUCLEAR RECEPTORS

Nettles, Kendall W., Greene, Geoffrey L.

Journal:

Annual Review of Physiology

Année:

2005

Langue:

english

Fichier:

PDF, 719 KB

english, 2005

CBP Is a Dosage-Dependent Regulator of Nuclear Factor-κB Suppression by the Estrogen Receptor

Nettles, Kendall W., Gil, German, Nowak, Jason, Métivier, Raphaël, Sharma, Vandana B., Greene, Geoffrey L.

Journal:

Molecular Endocrinology

Année:

2008

Langue:

english

Fichier:

PDF, 527 KB

english, 2008

The nuclear receptor signalling scaffold: insights from full-length structures

Nwachukwu, Jerome C, Nettles, Kendall W

Journal:

The EMBO Journal

Année:

2012

Langue:

english

Fichier:

PDF, 262 KB

english, 2012

SPIE Proceedings [SPIE Visual Communications and Image Processing '95 - Taipei, Taiwan (Tuesday 23 May 1995)] Visual Communications and Image Processing '95 - Multispectral imagery, hyperspectral radiometry, and unmanned underwater vehicles: tools for the assessment of natural resources in coastal waters

Costello, David K., Carder, Kendall L., Chen, Robert F., Peacock, Thomas G., Nettles, N. Sandy, Wu, Lance T.

Année:

1995

Langue:

english

Fichier:

PDF, 345 KB

english, 1995

Synthesis of novel steroidal agonists, partial agonists, and antagonists for the glucocorticoid receptor

Jin, Zhuang, Lin, Hua, Srinivasan, Sathish, Nwachukwu, Jerome C., Bruno, Nelson, Griffin, Patrick R., Nettles, Kendall W., Kamenecka, Theodore M.

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2017

Langue:

english

Fichier:

PDF, 2.01 MB

english, 2017

Exploring the Structural Compliancy versus Specificity of the Estrogen Receptor Using Isomeric Three-Dimensional Ligands

Sharma, Naina, Carlson, Kathryn E., Nwachukwu, Jerome C., Srinivasan, Sathish, Sharma, Abhishek, Nettles, Kendall W., Katzenellenbogen, John A.

Journal:

ACS Chemical Biology

Année:

2017

Langue:

english

Fichier:

PDF, 3.07 MB

english, 2017

Comparative Crystallographic Analyses

Nettles, Kendall W, Bruning, John B, Gil, German, Nowak, Jason, Sanjay, K, Hahm, Johnnie B, Kulp, Kristen, Hochberg, Richard B, Zhou, Haibing, John, a, Katzenellenbogen, Benita S, Kim, Younchang, Joac

Année:

2009

Langue:

english

Fichier:

PDF, 3.25 MB

english, 2009

Adamantyl Antiestrogens with Novel Side Chains Reveal a Spectrum of Activities in Suppressing Estrogen Receptor (ER)-Mediated Activities in Breast Cancer Cells

Min, Jian, Guillen, Valeria Sanabria, Sharma, Abhishek, Zhao, Yuechao, Ziegler, Yvonne, Gong, Ping, Mayne, Christopher G., Srinivasan, Sathish, Kim, Sung Hoon, Carlson, Kathryn E., Nettles, Kendall W.

Journal:

Journal of Medicinal Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 1.48 MB

english, 2017

Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes

Weikum, Emily R., de Vera, Ian Mitchelle S., Nwachukwu, Jerome C., Hudson, William H., Nettles, Kendall W., Kojetin, Douglas J., Ortlund, Eric A.

Journal:

Nucleic Acids Research

Année:

2017

Langue:

english

Fichier:

PDF, 3.55 MB

english, 2017

Cryptic glucocorticoid receptor-binding sites pervade genomic NF-κB response elements

Hudson, William H., Vera, Ian Mitchelle S. de, Nwachukwu, Jerome C., Weikum, Emily R., Herbst, Austin G., Yang, Qin, Bain, David L., Nettles, Kendall W., Kojetin, Douglas J., Ortlund, Eric A.

Journal:

Nature Communications

Année:

2018

Langue:

english

Fichier:

PDF, 2.62 MB

english, 2018

Pocket similarity identifies selective estrogen receptor modulators as microtubule modulators at the taxane site

Lo, Yu-Chen, Cormier, Olga, Liu, Tianyun, Nettles, Kendall W., Katzenellenbogen, John A., Stearns, Tim, Altman, Russ B.

Journal:

Nature Communications

Année:

2019

Fichier:

PDF, 3.21 MB

2019

Suppression of breast cancer metastasis and extension of survival by a new antiestrogen in a preclinical model driven by mutant estrogen receptors

Laws, Mary J., Ziegler, Yvonne, Shahoei, Sayyed Hamed, Dey, Parama, Kim, Sung Hoon, Yasuda, Mayuri, Park, Ben Ho, Nettles, Kendall W., Katzenellenbogen, John A., Nelson, Erik R., Katzenellenbogen, Ben

Journal:

Breast Cancer Research and Treatment

Année:

2020

Fichier:

PDF, 2.98 MB

2020